CASP1 and neoplasm: The pathway analysis results (Table 3E and Figure 5A) showed that normal tissue Treg and non-tumor diseased tissue Treg shared seven upregulated caspase-1 secretomic gene pathways including pathways in cancer, vesicle organization, negative regulation of apoptotic signaling, myeloid leukocyte activation, striated muscle cell differentiation, cell morphogenesis, and supramolecular fiber organization.