We also found 12 pathways associated with PD-1 non-collaboration genes shared by Treg in various groups (Figure 8E); 9 pathways associated with PD-1 non-collaboration genes shared by Treg in normal tissues; 13 pathways associated with PD-1 non-collaboration genes shared by Treg in non-tumor diseased tissues; and 22 pathways with PD-1 non-collaboration genes shared by Treg in tumor tissues. The gene discussed is PDCD1; the disease is neoplasm.