Tumor necrosis factor-alpha (TNF-α) and interleukin-1 beta (IL-1β) produced by inflamed immune cells such as tumor-associated macrophages (TAMs) promote the expression of inflammatory molecules in other cell types (Allavena et al., 2008; Sethi et al., 2008; Kore and Abraham, 2014). This evidence concerns the gene IL1B and neoplasm.