To this end, a monoclonal antibody against the CD200 protein (Samalizumab) (Adler, 2010) was evaluated in a clinical trial in 2008 for relapsed refractory B-cell chronic lymphocytic leukemia (B-CLL) and multiple myeloma (NCT00648739) (Adler, 2010). Here, CD200 is linked to B-cell chronic lymphocytic leukemia.