For example, it was found that lncRNA-UCA1 is involved in a typical ceRNA mechanism that influences the progression of colon cancer by forming the lncRNA-UCA1/Mir-28-5p/Hoxb3 axis, culminating in the regulation of gene function expression (Bánfai et al., 2012; Cui et al., 2019). Here, HOXB3 is linked to colonic neoplasm.