These included two genes previously determined to exhibit epilepsy phenotypes in zebrafish (e.g., scn1lab23 and stxbp1b homozygotes42) and six novel zebrafish epilepsy lines (e.g., arxa, eef1a2, gabrb3, pnpo, strada homozygotes, and grin1b heterozygotes). Here, PNPO is linked to epilepsy.