DNER and hepatocellular carcinoma: To study the effects of BET inhibitors on HCC growth, we treated HCC cell lines (HepG2 and Huh7) with BET inhibitors (JQ1 or OTX-015) at various concentrations (0.1 μM, 0.5 μM, 1.0 μM, 5.0 μM, and 10 μM) and different durations (6 h, 24 h, and 48 h).