Univariate analysis showed that age (p < 0.001), race (p = 0.023), marital status (p < 0.001), differentiation (p < 0.001), tumor size (p = 0.027), serum CEA (p < 0.001), PNI (p < 0.001), N classification (p < 0.001), LND number (p < 0.001), and adjuvant radiotherapy (p < 0.001) were associated with OS (Table 2). Here, CEACAM5 is linked to neoplasm.