CD274 and non-small cell lung carcinoma: In addition, a recent report regarding metastatic melanoma demonstrated that exosomal PD-L1 is associated with an anti-PD-1 response66, and another study revealed that the exosomal PD-L1 in the plasma of patients with non-small cell lung cancer was correlated with PD-L1 expression in tumor cells analyzed by the H-score67.