IFNG and tuberculosis: Interestingly, besides ESAT6/CFP10 (E/C), of which peptides are already widely used as TB diagnostic tool in IGRA tests27, Rv0287/88, Rv1886, Rv1131, Rv1221, Rv1846 and Rv3052 were the only antigens for which IFN-γ responses differed highly between the Mtb infected and the BCG vaccinated group (Fig. 2c).