In addition to the QPCR validation in human AML cell lines and primary AML blasts following KDM4A KD or PAF1 KD (Fig. 8B), we observed that the majority of KDM4A-9 genes show correlation with KDM4A and PAF1 expression in patient AML cohorts (Fig. 8C and D). Here, KDM4A is linked to acute myeloid leukemia.