Numerous work has already demonstrated the promising effect of FABP4 inhibition in preventing obesity, atherosclerosis, diabetes mellitus, metabolic syndrome, and AKI19,20,24, although recent work reported that FABP4 knockout mice improve kidney function and attenuate fibrotic response during kidney fibrosis22,23, the mechanistic function of pharmacological FABP4 inhibition has not yet been determined. Here, FABP4 is linked to diabetes mellitus.