REN and diabetes mellitus: Supplementary Table 2 shows the p-value of the associations between medication categories. Diuretic medication use was associated with most of the other medication categories, especially with the use of other antihypertensive medications (significant P range: 4.7 x 10-11 – 0.03). Also, the use of renin-angiotensin-aldosterone system (RAAS) inhibitors was associated with diabetes medication (P< 1 x 10-10). Both non-narcotic analgesic use and NSAID analgesic use were also significantly associated with several other medication use categories (significant P range: 9.6 x 10-10 – 0.03).