A higher hs-CRP level, a higher ApoB/ApoA1 ratio, DM, a higher monthly family income, HT, an increased frequency of fast food consumption, a lower HDL-C level, an increased frequency of hot pot consumption, hyperlipidaemia, a higher education level, a higher WHR, current smoking, and increased fertility among women were all associated with an increased risk of IS, and both manual work and moderate-intensity physical activity were associated with a reduced risk of IS. The gene discussed is APOA1; the disease is hyperlipidemia.