The expression trend of 83.2% of all DEGs including RPS27A, RPS21, RPS13, EEF1A1 and CYCS was reduced whereas the expression of 16.7% of all DEGs including SEMA6C, TPRF, NFATC4 and SMARCA2 was increased in CVT vs. CVO samples (Supplemental Fig. 1, Supplemental Table S6). Here, RPS21 is linked to congenital vertical talus.