The top 10 KEGG pathways significantly related to the tumorigenesis and progression of STAD were the cell cycle, oocyte meiosis, progesterone-mediated oocyte maturation, ubiquitin-mediated proteolysis, human T-lymphotropic virus type-1infection, foxO signaling pathway, vital carcinogenesis, p53 signaling pathway, small cell lung carcinoma, Epstein–Barr virus infection, and hepatitis B (Figure 8B). This evidence concerns the gene TP53 and gastric adenocarcinoma.