For instance, miR-92a-3p facilitates esophageal squamous carcinoma cell multiplication, migration and invasion by the regulation of phosphatase and tensin homolog (PTEN) [9]; miR-92a-3p functions as an oncomiR in glioma, and it promotes cancer cell proliferation via regulating Notch-1/Akt and CDH1/β-catenin signaling pathways [10]. This evidence concerns the gene PTEN and cancer.