Furthermore, although the abundance of the cDC1 hallmark transcripts, such as CLEC9A, in tumors correlates positively with cancer patient survival (Barry et al., 2018; Böttcher et al., 2018; Broz et al., 2014; Michea et al., 2018), it is unclear if this reflects a role of the corresponding gene products in cDC1-mediated anti-tumor immunity. This evidence concerns the gene MPPE1 and cancer.