Cytoplasmic gelsolin potentially released from dead cells was also not sufficient to interfere with DNGR-binding as the reporter cells were stimulated equally by killed cells from the parental (gelsolin-sufficient) 5555 BrafV600E tumor cell line and from a stable 5555 BrafV600E gelsolin knockdown (KD) line (Figures 2D and S2B). This evidence concerns the gene GSN and neoplasm.