As our freshly excised and TIL-PDX–derived tumor tissues were not always from the same donor, it is not possible to determine whether this reduction in PD-L1 and increase in PD-1 expression are due to patient-to-patient variation or whether factors that drive PD-L1/PD-1 expression on human NK cells, T cells, and LUAD in humans are reduced in TIL-PDX mice. Here, CD274 is linked to neoplasm.