The data and images indicated a reduction in LVIDD, LVIDs, LVEF, LVFS, LVEDP, and +dP/dt in MI mice which were injected with AgomiR-22-3p, and an improvement in cardiac function in MI mice injected with AntagomiR-22-3p and sh-Ltb4r1 (Figure 3A, 3B). Here, LTB4R is linked to myocardial infarction.