As shown in Table 2, univariate LR analysis of RA patients developing stroke indicated that the stratification of sex, age, SBP, CRP, ESR, TC, LDL and the history of hypertension, diabetes, AF, CVD, and CHD, were significantly different between RA with stroke and RA groups (P < 0.05) in the primary cohort. This evidence concerns the gene CRP and diabetes mellitus.