As shown in Table 2, univariate LR analysis of RA patients developing stroke indicated that the stratification of sex, age, SBP, CRP, ESR, TC, LDL and the history of hypertension, diabetes, AF, CVD, and CHD, were significantly different between RA with stroke and RA groups (P < 0.05) in the primary cohort. The gene discussed is CRP; the disease is rheumatoid arthritis.