Recently, direct associations between high glucose, monocytes, and SARS-CoV-2 infection were reported; single cell RNA-seq data from bronchoalveolar lavage (BAL) fluid of COVID-19 patients and controls identified that several genes associated with “interferon (IFN) α/β signaling pathway” were upregulated in mild and severe COVID-19 patients vs. controls in all 6 clusters of monocytes [39]. This evidence concerns the gene IFNA1 and COVID-19.