A prospective exploratory study evaluating multiple cytokines has shown that a cutoff value of 6.53 pg/mL for IL6 and 60.8 pg/mL for IL8 was associated with overall survival irrespective of tumor entity after 90Y radioembolization (RE) in patients with HCC or metastatic disease [9]. This evidence concerns the gene CXCL8 and hepatocellular carcinoma.