IL2 and glioblastoma: To mimic potential immunostimulatory effects of circulating Hsp70 in glioblastoma patients, PBL of healthy human donors (n = 4) were stimulated in vitro either with TKD/IL-2 (TKD) or Hsp70/IL-2 (Hsp70) (Multhoff et al., 1999; Multhoff et al., 2001).