No significant difference was observed in IL-6 and IL-8 levels between the two groups, whereas several metabolites were more concentrated in the vaginal environment of women who suffered a miscarriage (i.e., xanthine, p = 0.01; benzoate, p = 0.02, 4-hydroxyphenyllactate, p = 0.02; fumarate, p = 0.001; inosine, p = 0.004; UDP, p = 0.03; ascorbate; p = 0.01; ethanolamine, p = 0.02). The gene discussed is CXCL8; the disease is Miscarriage.