Likewise, we found that B7H3 was dramatically declined in both IDH-mutated LGG (n = 133) and GBM (n = 41) compared with that in the corresponding IDH-WT LGG (n = 48, p < 0.001) and GBM (n = 98, p < 0.001) in CGGA database (Figure 1A). This evidence concerns the gene CD276 and glioblastoma.