A risk score was then computed for each DLBCL patient based on the individual expression of the seven CIFs, weighted by the regression coefficient in the training set based on the following formula: risk score = (0.0668 × CCL2 expression) + (−0.2463 × CSF2 expression) + (0.05391 × IL15 expression) + (-0.2381 × IL17A expression) + (-0.2305 × IL4 expression) + (-0.1621 × TGFA expression) + (-0.1621 × TNFSF10 expression). This evidence concerns the gene CSF2 and diffuse large B-cell lymphoma.