This result was shown in another study in which the researchers analyzed the expression of FRα in 27 lung cancer cell lines, including 19 LUAD, 1 lung squamous cell carcinoma (SqCC), 1 lung adenosquamous carcinoma (ASC), 3 small cell lung cancer (SCLC) and 3 lung large cell carcinoma (LCC) cell lines, and only observed strong bands in the Western blots of A549 (LUAD), H647 (ASC), H460 (LCC) and SBC-5, KB (SCLC) cell lines, whereas other cell lines had faint or no bands, especially LUAD cell lines (24). The gene discussed is FOLR1; the disease is leukoencephalopathy with calcifications and cysts.