Firstly, for the CD14+ monocytes in RA, we detected enrichment of abnormally methylated DEGs like “viral process,” “cell proliferation,” “positive regulation of transcription from RNA polymerase II promoter,” “energy reserve metabolic process,” and “negative regulation of sequence-specific DNA binding transcription factor activity” GO terms in biological processes (Figure 9A). The gene discussed is CD14; the disease is rheumatoid arthritis.