Firstly, for the CD4+ T cells in RA, we detected the aberrantly methylated DEGs enrichment related to “angiogenesis,” “regulation of cell shape,” “negative regulation of transcription from RNA polymerase II promoter,” “negative regulation of cell migration,” and “cellular response to cAMP” GO terms for biological processes (Figure 6A). This evidence concerns the gene CD4 and rheumatoid arthritis.