Except for the ROC values of CENPE (p = 0.006), TOP2A (p = 0.0208), PBK (p = 0.0019), and KIF11 (p = 0.0095) genes expressed in the T cells of SLE, all the other genes in SLE and RA had p values < 0.0001. This evidence concerns the gene TOP2A and systemic lupus erythematosus.