VEGFA and Abnormal retinal morphology: In light of the criticality of both angiogenesis and vessel leakage in retinal disease, these processes should be studied in the context of galectins; in particular, in light of the success and the limitations of anti-VEGF treatment, pointing on the one hand to the clinical feasibility of anti-angiogenic treatment and, on the other hand to the existence of redundant and/or refractory pathways.