To determine whether Trpv1 expression may contribute to the epilepsy phenotype of Scn1a+/− mice, we compared the cortical mRNA levels from WT and Scn1a+/− mice on both 129S6/SvEvTac (129) and on [129S6/SvEvTac × C57BL/6J]F1 (129 × B6) genetic backgrounds. Here, SCN1A is linked to epilepsy.