LIMK1 and neoplasm: Compared with levels in stage I or grade 1 BC tumor, LIMK1 mRNA levels were much higher in stage II (P = 0.0146) or grade 2 (P = 0.0013) and stage III (P < 0.0001) or grade 3 (P < 0.0001) BC tumor tissues (Fig. 4C, D).