Our data revealed that loss of MLKL resulted in an expansion of progenitor populations in primary murine BM (Figs. 2A–C, S2D), which was mainly driven by increased numbers of CMP implying that MLKL contributed to the myeloid differentiation of progenitor cells in AML (Figs. 2D–F, S2D). The gene discussed is MLKL; the disease is acute myeloid leukemia.