The differential expression analysis of 5561 proteins in 95 colorectal adenocarcinoma (COAD) samples indicated high levels of TAP2 (log Fold Change [FC] = -1.33), PARP14 (logFC = -1.25), and GBP4 (logFC = -1.09) in the RSI-Low tumours (Supplementary Fig. 8a and Supplementary Table 1). This evidence concerns the gene GBP4 and neoplasm.