NMI and breast cancer: Hence, we examined the enriched gene signature from the GSEA with RNA-seq data obtained from NMI wild-type and knockout mammary tissue (Fig. 5a); as well as with RNA-seq data obtained from overexpression and silencing of NMI in human breast cancer cell lines MDA-MB-231 and T47D, respectively, to determine if some consistent common genes emerge (Fig. 5b).