In support of this, recent studies have shown that IL-13 acts to mediate recovery and repair in the gut following dextran sulphate sodium (DSS)-induced colitis, which is Th1 driven, as disease was improved in both IL-13Rα2 KO mice and in mice treated with a neutralizing IL-13Rα2 antibody (Karmele et al., 2019). The gene discussed is IL13RA2; the disease is colitis.