Furthermore, while previous studies (Lamers et al., 2013; van Reedt Dortland et al., 2010) investigating the biological correlates of depression subtypes commonly examined a very limited number of biomarkers, we used an extensive lipid focused metabolomics platform (149 metabolites) and 12 cardiometabolic diseases, including four extensive adiposity measures, glucose, insulin and lipoprotein measures. The gene discussed is INS; the disease is depressive symptom measurement.