But to give evidence for a pre-manifestation of PD in the gut in the 2-month-old mice, we identified disease causing overexpressed α-synuclein aggregates (human A30P α-synuclein) in the small and the large intestine of both, 2-month-old PD and WT mice, using Paraffin immunofluorescence. Here, SNCA is linked to Parkinson disease.