Autoimmune polyendocrinopathy-candidiasis-ectodermal-dystrophy (APECED) also known as autoimmune polyglandular syndrome Type 1 (APS-1) [1] is a rare autosomal recessive disorder caused by mutations in the Autoimmune Regulator (AIRE) gene [2]. This evidence concerns the gene AIRE and Autoimmune polyendocrinopathy type 1.