Patients with VTE (DVT ± PE; n = 3, PE n = 5) were older, had higher peak plasma values of C-reactive protein (CRP), D-dimer and creatinine but no statistically significant difference in peak plasma values of troponin I and N-terminal pro brain natriuretic peptide (NT-pro-BNP) compared to patients without VTE (n = 48) (Table 2). This evidence concerns the gene NPPB and deep vein thrombosis.