To further address these unknown issues, we aimed to explore the expression of TRPA1 and TRPV1 in the jugular ganglia and nodose ganglia and that of neurogenic indicators such as SP, CGRP, and NK1R in the lungs using an established guinea pig cough model of pulmonary fibrosis induced with bleomycin. The gene discussed is TFF2; the disease is pulmonary fibrosis.