Increased expression of TRPA1\TRPV1 in the jugular ganglion and nodose ganglia of the guinea pig model of bleomycin-induced pulmonary fibrosis suggests that such up-regulated expression of TRPA1\TRPV1 on the cough afferent pathway might be associated with the increased cough sensitivity in animal models; however, a previous study [31] showed that there is unchanged mRNA expression of TRPV1 and TRPA1 in the lung. This evidence concerns the gene TRPV1 and pulmonary fibrosis.