HSP90AB1 and cancer: Given the dual role of HSP90 in folding/stabilizing many kinases and in mediating drug resistance (Taipale et al., 2012; Wang et al., 2016; Workman et al., 2016), simultaneous inhibition of HSP90 and therapeutically important kinases could be an interesting strategy to prevent or delay the persistent problem of cancer drug resistance (Anighoro et al., 2014; Das et al., 2018; Schwartz et al., 2015; Workman et al., 2016).