Besides, TROAP indicated significant hyper‐expression in glioblastoma stem cells (GSCs, especially in mesenchymal GSCs) and GBM cells compared with neuro stem cells (NSCs) and normal human astrocyte (NHA), suggesting that TROAP had the potential to promote the malignant phenotype of glioma (GSE67089, Figure 1F). This evidence concerns the gene TROAP and central nervous system cancer.