Soluble MICA was found significantly elevated in the sera of patients with leukemia [43,44], colorectal cancer [45], prostate cancer [46], lung cancer, ovarian cancer, prostate cancer, breast cancer [47], pancreatic cancer [48,49], oral squamous cell cancer [50,51] and hepatocellular cancer [52]. The gene discussed is MICA; the disease is pancreatic neoplasm.