CIPC and acute kidney injury: In a pilot study reported in 2015, Lin et al. found that three lncRNAs, namely MIR210HG, linc-ATP13A4–8, and linc-KIAA1737–2, were upregulated in human proximal tubular epithelial cells after challenged with hypoxia, pro-inflammatory cytokines or plasma from severe septic patients, proposing that these lncRNAs might be involved in the development of sepsis-induced acute kidney injury (Lin et al. 2015).