Using miRanda software we found that Linc-KIAA1737–2 might interact with miR-27a-3p, and we hypothesized that Linc-KIAA1737–2 might facilitate LPS-induced HK-2 cell apoptosis as well as sepsis-induced acute kidney injury by sponging and inhibiting miR-27a-3p. Here, CIPC is linked to acute kidney injury.