Wiegreffe et al (2015) found that homozygous mutant Bcl11a mice presented defects in neuronal morphology and neuronal migration, and that the mutant phenotype was rescued when knocking down Sema3c. Of note, a de novo microdeletion in the dyslexia susceptibility locus 3 (DYX3) on chromosome 2p spanning only the BCL11A gene was reported in a proband with severe speech sound disorder (Peter et al. 2014). The gene discussed is SEMA3C; the disease is dyslexia.