Corticosteroids are extensively used to treat asthma and chronic obstructive pulmonary disease because of their strong anti‐inflammatory ability, which is attributed to the repression of target pro‐inflammatory gene transcription through inhibiting nuclear factor‐κB (NF‐κB) and activator protein‐1 (AP‐1) activation.41 This evidence concerns the gene NFKB1 and asthma.