HNRNPM dependency appeared similar in the PC3 PCa cell line (Figure 2—figure supplement 1B–F), which bears different driver mutations (PTEN null, TP53 null, androgen independent) from LNCAP (PTEN null, TP53 wildtype, androgen dependent) (van Bokhoven et al., 2003). This evidence concerns the gene TP53 and posterior cortical atrophy.