To better understand the impact of reduced HNRNPM binding in PCa cells, we further performed RNA sequencing on LNCAP PCa cells that were transduced either with the scrambled shRNA or HNRNPM-specific shRNAs (2B7 and 2B9; n = 3 replicates per shRNA) (Figure 4A, Figure 4—source data 1). The gene discussed is HNRNPM; the disease is posterior cortical atrophy.