An additional possible pathomechanism, referring to the different substrate specificity of NAA10, was proposed by Stove et al., who published a previously undescribed maternally inherited NAA10 variant Ile72Thr in three boys from two unrelated families with a milder phenotypic spectrum consisting of developmental delay, intellectual disability, cardiac arrhythmia and hypertrophic cardiomyopathy (Stove et al., 2018). This evidence concerns the gene NAA10 and cardiac arrhythmia.