Intriguingly, a high expression level of RHOBTB2 was associated with poor overall survival (OS) (Hazard ratio (HR) (high) = 2.9; P = 0.00041, Figure 2B) while a low expression level of RHOBTB3 was associated with poor OS for patients with AML (HR (high) = 0.44; P = 0.0045, Figure 2C) in GEPIA2. The gene discussed is RHOBTB3; the disease is acute myeloid leukemia.