In line with expectations, the expression coefficients of some immune cell markers (such as ARG1, CD14, BCL6, CCR3, and CDR10) and C12orf75 were opposite to the expression coefficients of immune cells as a whole and C12orf75, which indicates that some specific immune cell subtypes may interact with C12orf75. In BLCA, there was a clear positive correlation between macrophage infiltration and C12orf75 expression, and the infiltration of CD8+ T cells, which is positively correlated with C12orf75 expression, was dominated by Th1 (T helper 1 cells) and Treg (T regulatory cells). Here, CD8A is linked to bladder transitional cell carcinoma.