The Multi-Ethnic Study of Atherosclerosis (MESA), also found heterogeneity of effects across ethnic groups and ethnic-specific results while investigating genetic associations of body mass index (BMI); in particular the intronic rs6435678 in ERBB4 on chromosome 2 was significantly associated with BMI only in AA; however, these results were uncorrelated with our significant chromosome 2 associations with weight in the GENNID EA families [74]. This evidence concerns the gene ERBB4 and atherosclerosis.