The ADIPOQ gene was nominated as a candidate gene in our linkage region on 3p26 [32]; however, in the current study there was no evidence of associated QTNs in the ADIPOQ region with any of the univariate MetS traits, despite previous reports of ADIPOQ being associated with multiple underlying MetS conditions [8] and being associated with MetS in Han Chinese [69] and North Indian Punjabi [70]. This evidence concerns the gene ADIPOQ and metabolic syndrome.